Blog: Prediction Markets for Science: Beyond the Quick Bucks
Throughout the 2024 US election season, as opinion polls predicted roughly even chances of either party winning, news media paid special attention to the odds on prediction markets such as Polymarket.
More recently, prediction markets made headlines for a different reason. When Venezuelan President Maduro was captured in January 2026, the prediction market reacted quicker than the actual news, helping a lucky insider make $436,000 in a few hours.
But what are some uses for scientists, besides making some (or half a million) quick bucks?
Determining the Reproducibility of Scientific Studies
Several studies have explored the use of market-based prediction of reproducibility to guide scientific funding and replication efforts.
Dreber et al. (2015) created their own prediction markets with recruited participants during psychology's Reproducibility Project, effectively leveraging the wisdom of the crowd with real financial stakes. The predictions coming from the prediction market were more accurate and more confident than those from a survey—even with the same participants. Market prices correctly predicted replication outcomes 71% of the time, compared to just 58% for surveys.
A Scientific Funding Market That Rewards Discovery and Disclosure
Almenberg et al. (2009) conducted an experiment with three information settings:
- Everyone had the same information
- Some people had privileged information
- Some people had privileged information that would later be made public
They found that Setting 3 combined the best of the two other settings: the prediction probabilities were as accurate as in Setting 1, and the privileged people (scientists who gained information asymmetry through their research) were able to reap a profit.
The researchers entertained the idea that this could become a new funding structure for science: a market-based approach that allows funding agencies to identify the most viable projects and scientists to be financially incentivized to produce and make public their quality research.
The Manipulation Problem
Of course, prediction markets have their limitations, especially given that financial incentives can encourage participants to manipulate the outcome or its metrics. For example, an unauthorized edit on the interactive war map of Institute for the Study of War showed an incredibly swift Russian advance into Myrnohrad. Since the map was used by Polymarket to determine the outcome of a bet, a few betters bagged a 33,000% return.
Despite the imperfections, prediction markets are poised to become integrated with the mainstream financial system and evolve into a powerful tool for opinion polling and forecasting—one that works best when incentives align with societal goals and outcomes are protected from manipulation.
This blog post is a recap of Jianlong Zhu's presentation in the I2SC group meeting on 4 Feb 2026.
References:
- Dreber, A., Pfeiffer, T., Almenberg, J., et al. (2015). "Using prediction markets to estimate the reproducibility of scientific research." PNAS, 112(50), 15343-15347.
- Almenberg, J., Kittlitz, K., & Pfeiffer, T. (2009). "An Experiment on Prediction Markets in Science." PLOS ONE, 4(12), e8500.